Research Overview

Activities in my research group focus on chemical and biological systems. This entails carrying out experiments in the laboratory, developing mathematical models and solving the models in single or multiple objective optimization frameworks. Experiments for elucidating the genetic aspects in azo dye degradation and mineralization of aromatic amines using novel bacterial consortium that will ultimately lead to novel remediation process; use of evolutionary (e.g., GA) and global optimization (e.g., BB, OA) techniques in graph-theoretic framework for array informatics (gene expression profiling and gene network analysis from cDNA microarray data); RNA interference using siRNA for neurodegenerative diseases; rational drug design (reverse engineering the structures of lead candidates from quantitative structure activity relationships) and reverse engineering the suitable biodegradable and biocompatible polymers for local and controlled drug delivery are some of the current research activities going on in the group.