Rivers and especially large rivers are one of the most important geomorphic systems, on which the sustainability of modern society is dependent. In spite of the pivotal role rivers play in sustaining human civilizations, the understanding of large river systems and appreciation of their multidimensional nature is still fragmentary. Our research in river science encompasses a wide gamut of topics ranging from river morphodynamics, flood risk and sediment flux measurements. One of our important activities is to probe the anthropogenic transformations of large river systems in terms of river form and processes. Also assessing how climate change affects the linkages between the Himalayan cryosphere and large-river systems are of interest.