CHM689A

Nuclear Magnetic Resonance

Spectroscopy

CHM689A

3-0-0-9

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Course Contents

Introduction to NMR Spectroscopy.(1)

Angular momentum, matrix representation of angular momentum operators. (6)

Density matrices, pure and mixed states, density operator and calculation of expectation values.(6)

Chemical shifts, coupling constants, rotating frame concept and qualitative description of pulse experiments.(5)

Construction of hamiltonian matrix for multispin systems and the solution of AB and ABX spin systems.(5)

Product operator formalism and vector diagrams.(5)

Analysis of multipulse experiments: INEPT, DEPT, COSY, NOESY and double quantum filtered COSY. (12)

Multidimensional NMR and macromolecular structure determination. (2)

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+ - Books and References Click to collapse

M.Goldman, Quantum Description of High Resolution NMR in Liquids, Clarendon Press, New York(1988).
J.A.Pople, W.G.Schneider and H.J.Bernstein, High Resolution NMR, McGraw Hill, New York(1959).
J.Cavanagh, W.J.Fairbrother, A.G.Palmer III and N.J.Skelton, Protein NMR Spectroscopy, Academic Press(1996).
C.P.Slichter, Principles of Magnetic Resonance, Springer-Verlag, Berlin(1990).

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