Prerequisites:
CHM201N for M.Sc. Int. students
CHM102 for BS/MS students(newARC)
Course Contents
Benzil – Benzilic Acid Rearrangement
(a) Prep. of benzil by oxidation of benzoin by nitric acid
(b) Benzil, an ® , ¯ - diketone undergoes rearrangement to benzilic acid.
Fisher: Indole Synthesis: Preparation of 1.2.3.4 – tetrahydrocarbazole. This compound is prepared according to the Fisher indole synthesis starting from phenylhydrazine and cyclohexanone.
Diazotization: Forming a diazonium salt from an appropriate primary aromatic amine in the presence of HNO2.
Preparationof P-Iodonitrobenzene: p-Nitroaniline is diazotized and treated with KI
PHOTOCHEMICALREACTIONS: By Irradiation with Sunlight OR By Reductive Coupling
Prep. of Benzopinacol from benzophenone by reductive coupling
MOLECULARREARRANGEMENT
Pinacol – Pinacolone – rearrangement
(a) Prep. of benzopinacol
(b) Prep. of benzopinacolone
REIMER – TIEMANNREACTION
Prep. of β-hydroxynapthaldehyde from β-napthal
PERKINREACTION
Preparation of Cinnamic acid
Bromination cinnamic acid i.e. Prep. of bromostryrene
ALDOLCONDENSATIONANDEPOXIDATION
(a) Preparation of Chalcone
(b) Preparation of Chalcone epoxide
